CBE Best Paper of the Year Award Winner: Carolyn Shurer, Paszek Group
"Physical Principles of Membrane Shape Regulation by the Glycocalyx" Brief synopsis: In Physical Principles of Membrane Shape Regulation by the Glycocalyx, published in Cell in Shurer et. al. model the glycocalyx as a classic polymer brush; and we show for the first time how glycocalyx biopolymers can drive membrane bending via an entropic force into various membrane morphologies including membrane projections and vesicles. Both intracellular dynamics and glycocalyx-imposed forces work together to regulate membrane shapes. Read more