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Singh named the 2014 Young Innovator

Tuesday, July 29, 2014

The entire microarray is of the size of a quarter dollar with more than 1,300–1,500 microwells (~400 µm wide) each of which are composed of bioadhesive hydrogels encapsulating cancer cells. Red: Leukemia cells. Green: Cervical cancer cells. Source: Ankur Singh

Cornell Engineering’s Ankur Singh is among 13 outstanding U.S. scientists recently recognized as 2014 Young Innovators in Cellular and Molecular Bioengineering.

Singh’s peer-reviewed research on “Microscale bioadhesive hydrogel arrays for cell engineering applications” will be published in the journal’s Young Innovators issue and the assistant professor of mechanical and aerospace engineering has been invited to present the work at the 2014 Fall Biomedical Engineering Society Conference in San Antonio, Oct 22–25.

Singh and his group have engineered microarrays of cell adhesive microenvironments to study cervical and leukemia tumor cell behavior and survival. Such microenvironments are modular and have the ability to change mechanical properties independent of the adhesivity providing a unique insight into cell survival mechanism. These hydrogels could also function as building blocks to fabricate 3D tissue structures, cell delivery systems, and high throughput drug screening devices.

Singh Lab researchers Ravi Patel (MAE) and Alberto Purwada (BME) participated in the research. The study was funded by the National Institutes of Health the National Cancer Institute, and the Cornell-Weill Cornell Medical College seed funding awarded to Singh and his collaborators.

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