Shotgun scanning glycomutagenesis: A simple and efficient strategy for constructing and characterizing neoglycoproteins
Matt DeLisa, the William L. Lewis Pressor of Engineering and Director of the Cornell Institute of Biotechnology, published a new study in the Sep. 28 issue of PNAS. The study, "Shotgun scanning glycomutagenesis: A simple and efficient strategy for constructing and characterizing neoglycoproteins," focuses on a glycoprotein engineering strategy that enables systematic investigation of the structural and functional consequences of glycan installation at every position along a protein backbone and provides a new route to bespoke glycoproteins. Asparagine-linked (N-linked) protein glycosylation... Read more